KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPOLA
All Species:
36.97
Human Site:
T223
Identified Species:
73.94
UniProt:
P51003
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51003
NP_116021.2
745
82843
T223
N
I
D
N
F
R
L
T
L
R
A
I
K
L
W
Chimpanzee
Pan troglodytes
XP_515496
714
80108
T222
N
K
E
T
F
R
L
T
L
R
A
V
K
L
W
Rhesus Macaque
Macaca mulatta
XP_001101831
825
90125
S201
L
D
I
R
C
I
R
S
L
N
G
C
R
V
T
Dog
Lupus familis
XP_537551
812
90509
T296
N
I
D
N
F
R
L
T
L
R
A
I
K
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q61183
739
82291
T223
N
I
D
N
F
R
L
T
L
R
A
I
K
L
W
Rat
Rattus norvegicus
NP_001101526
739
82082
T223
N
I
D
N
F
R
L
T
L
R
A
I
K
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511509
736
82218
T220
N
I
D
N
F
R
L
T
L
R
A
I
K
L
W
Chicken
Gallus gallus
XP_421352
737
82879
T222
N
I
D
N
F
R
L
T
L
R
A
I
K
L
W
Frog
Xenopus laevis
P51004
715
80169
T205
N
I
D
S
F
R
L
T
L
R
A
I
K
L
W
Zebra Danio
Brachydanio rerio
NP_991321
723
80246
T222
N
I
E
N
F
R
L
T
L
R
A
I
K
L
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393202
615
69546
R130
V
V
P
R
H
I
Y
R
S
D
Y
F
T
S
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29468
568
64534
K83
M
A
R
D
A
G
G
K
I
F
T
Y
G
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.8
78.4
89.7
N.A.
95.5
95
N.A.
95.5
89.9
80.1
70.3
N.A.
N.A.
49.7
N.A.
N.A.
Protein Similarity:
100
72.6
80.7
90.1
N.A.
97.4
96.7
N.A.
96.9
93.8
86.3
80
N.A.
N.A.
62.2
N.A.
N.A.
P-Site Identity:
100
73.3
6.6
100
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
86.6
26.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
0
0
0
75
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
59
9
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
75
0
0
0
0
9
0
9
0
0
9
% F
% Gly:
0
0
0
0
0
9
9
0
0
0
9
0
9
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
67
9
0
0
17
0
0
9
0
0
67
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
9
0
0
0
0
75
0
0
% K
% Leu:
9
0
0
0
0
0
75
0
84
0
0
0
0
75
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
75
0
0
59
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
17
0
75
9
9
0
75
0
0
9
0
0
% R
% Ser:
0
0
0
9
0
0
0
9
9
0
0
0
0
17
0
% S
% Thr:
0
0
0
9
0
0
0
75
0
0
9
0
9
0
9
% T
% Val:
9
9
0
0
0
0
0
0
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
9
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _